STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAB5CUncharacterized protein. (216 aa)    
Predicted Functional Partners:
RABGEF1
Uncharacterized protein.
   
 0.972
PIK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
    
 0.963
VPS18
VPS18 core subunit of CORVET and HOPS complexes.
   
 0.954
VPS16
Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.
    
 0.953
VPS8
VPS8 subunit of CORVET complex.
    
 0.951
TGFBRAP1
Transforming growth factor beta receptor associated protein 1.
    
 0.949
VPS11
Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.
    
 0.948
VPS33A
Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.
    
 0.936
EEA1
Early endosome antigen 1.
    
 0.929
RIN1
Ras and Rab interactor 1.
    
 0.923
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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