STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDCD5Programmed cell death 5. (197 aa)    
Predicted Functional Partners:
ENSFCAP00000037913
Uncharacterized protein.
  
    0.851
RPL23
Ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family.
   
  
 0.825
PFDN1
Prefoldin subunit 1.
   
    0.784
ENSFCAP00000033817
Uncharacterized protein.
   
    0.768
SNRPE
Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development.
   
    0.768
SALL4
Spalt like transcription factor 4.
      
 0.760
UVRAG
UV radiation resistance associated.
      
 0.759
PFDN4
Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family.
   
   0.756
EEF1B2
Eukaryotic translation elongation factor 1 beta 2; Belongs to the EF-1-beta/EF-1-delta family.
   
    0.713
EEF1D
Eukaryotic translation elongation factor 1 delta; Belongs to the EF-1-beta/EF-1-delta family.
   
    0.713
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.