Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TIAM1T cell lymphoma invasion and metastasis 1. (1591 aa)    
Predicted Functional Partners:
PARD3
Par-3 family cell polarity regulator.
    
 0.974
RAC1
Rac family small GTPase 1.
    
 0.961
RAC2
Rac family small GTPase 2.
    
 0.952
PAK1
Non-specific serine/threonine protein kinase.
   
 0.943
VAV2
Vav guanine nucleotide exchange factor 2.
     
0.937
CD44
CD44 molecule (Indian blood group).
    
 0.933
PRKCZ
Protein kinase C zeta.
    
 0.921
VAV1
Vav guanine nucleotide exchange factor 1.
     
 0.917
RAC3
Rac family small GTPase 3.
    
 0.916
KRAS
Uncharacterized protein.
    
 0.913
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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