STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC11A1Solute carrier family 11 member 1. (547 aa)    
Predicted Functional Partners:
SLC11A2
Solute carrier family 11 member 2.
  
  
0.909
S100A12
EF-hand domain-containing protein; Belongs to the S-100 family.
   
 
 0.820
USP40
USP domain-containing protein; Belongs to the peptidase C19 family.
     
 0.690
IL1RN
Interleukin-1.
   
  
 0.669
CSN3
Kappa-casein; Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk; Belongs to the kappa-casein family.
   
  
 0.535
TYROBP
TYRO protein tyrosine kinase binding protein.
   
  
 0.529
PYCARD
PYD and CARD domain containing.
   
  
 0.513
TCIRG1
V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
   
 
 0.510
COMMD5
COMM domain containing 5.
      
 0.488
NOD2
Nucleotide binding oligomerization domain containing 2.
   
  
 0.487
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.