STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UBR1E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1753 aa)    
Predicted Functional Partners:
TRIP12
Thyroid hormone receptor interactor 12.
   
 0.976
UBR4
Ubiquitin protein ligase E3 component n-recognin 4.
   
  
 0.850
UBR5
Ubiquitin protein ligase E3 component n-recognin 5.
   
  
 0.816
LTN1
Listerin E3 ubiquitin protein ligase 1.
   
 0.770
ENSFCAP00000026617
Ubiquitin-like domain-containing protein.
   
 0.722
UBE2W
UBIQUITIN_CONJUGAT_2 domain-containing protein.
   
 
 0.717
ATAD2B
ATPase family AAA domain containing 2B.
   
 
 0.698
PHIP
Pleckstrin homology domain interacting protein.
   
 
 0.697
FBXL20
F-box domain-containing protein.
   
  
 0.692
WASHC4
WASH complex subunit 4.
   
    0.687
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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