STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACER2Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)    
Predicted Functional Partners:
ASAH2
Neutral ceramidase.
    
 0.968
CERK
Ceramide kinase.
    
 0.960
SPHK1
Sphingosine kinase 1.
    
 0.958
ASAH1
N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family.
     
 0.956
SPHK2
DAGKc domain-containing protein.
    
 0.955
CERS4
Ceramide synthase 4.
    
 0.954
CERS6
Ceramide synthase 6.
    
 0.953
SGMS1
Sphingomyelin synthase 1.
     
 0.948
CERS5
Ceramide synthase 5.
    
 0.947
CERS2
Ceramide synthase 2.
    
 0.946
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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