STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HTRA4HtrA serine peptidase 4. (476 aa)    
Predicted Functional Partners:
SCP2
Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family.
    
 0.768
LEPROTL1
Leptin receptor overlapping transcript like 1.
      
 0.697
NAA30
N(alpha)-acetyltransferase 30, NatC catalytic subunit.
      
 0.693
BIRC6
Baculoviral IAP repeat containing 6.
    
 0.685
KATNAL2
Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.
   
 0.664
PSMD1
26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.
    
 0.638
XIAP
X-linked inhibitor of apoptosis.
    
 0.636
EPHX2
Epoxide hydrolase 2.
  
 
 0.636
TM2D2
TM2 domain containing 2.
      
 0.635
PSMD12
Proteasome 26S subunit, non-ATPase 12.
    
 0.611
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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