Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SLIT1Slit guidance ligand 1. (1518 aa)    
Predicted Functional Partners:
ROBO2
Roundabout guidance receptor 2.
   
 0.976
ROBO1
Roundabout guidance receptor 1.
   
 0.957
ROBO4
Roundabout guidance receptor 4.
   
 0.948
ROBO3
Roundabout guidance receptor 3.
    
 0.891
NTN1
Netrin 1.
    
 0.741
SEMA3F
Semaphorin 3F; Belongs to the semaphorin family.
      
 0.671
NEO1
Neogenin 1.
   
 0.661
SEMA6D
Semaphorin 6D; Belongs to the semaphorin family.
      
 0.611
GDNF
Glial cell derived neurotrophic factor.
     
 0.599
DAG1
Peptidase S72 domain-containing protein.
   
 
  0.556
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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