STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPTBSpectrin beta chain; Belongs to the spectrin family. (2326 aa)    
Predicted Functional Partners:
SPTA1
Spectrin alpha, erythrocytic 1.
   
0.966
SPTAN1
Spectrin alpha, non-erythrocytic 1.
   
0.858
TMOD1
Tropomodulin 1.
   
  
 0.621
ITSN2
Intersectin 2.
     
 0.612
ALAD
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
      
 0.603
COPB1
Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
    
 0.588
STX2
Syntaxin 2; Belongs to the syntaxin family.
   
  
 0.581
PROP1
PROP paired-like homeobox 1.
      
 0.577
EPB41
Erythrocyte membrane protein band 4.1.
   
 0.577
ANK2
Uncharacterized protein.
   
 0.572
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.