STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CORO1BCoronin; Belongs to the WD repeat coronin family. (488 aa)    
Predicted Functional Partners:
SLK
STE20 like kinase.
   
  
 0.712
HIPK4
Homeodomain interacting protein kinase 4.
      
 0.705
CORO1C
Coronin; Belongs to the WD repeat coronin family.
  
 
 
0.697
OSTF1
Uncharacterized protein.
   
 
 0.689
ACTR2
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
   
 
 0.688
WIPF1
WAS/WASL interacting protein family member 1.
   
 
 0.634
EXOC4
Exocyst complex component 4.
      
 0.623
DHFR
DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.
    
 0.612
WDFY2
WD repeat and FYVE domain containing 2.
   
 
 0.591
CFL2
Cofilin 2; Belongs to the actin-binding proteins ADF family.
   
 
 0.573
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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