STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMPDL3BThymocyte selection associated family member 2. (752 aa)    
Predicted Functional Partners:
XKR8
XK-related protein.
      
 0.747
PACSIN2
Protein kinase C and casein kinase substrate in neurons 2.
      
 0.721
TCIRG1
V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
   
  
 0.648
PCGF5
Polycomb group ring finger 5.
      
 0.608
ECEL1
Endothelin converting enzyme like 1.
      
 0.603
SYTL1
Synaptotagmin like 1.
      
 0.603
GRB2
Growth factor receptor bound protein 2.
   
 
 0.560
BATF2
Basic leucine zipper ATF-like transcription factor 2.
   
  
 0.558
PLEKHO2
PH domain-containing protein.
   
  
 0.557
TNFSF15
TNF superfamily member 15.
      
 0.541
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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