STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TTC22Tetratricopeptide repeat domain 22. (569 aa)    
Predicted Functional Partners:
SPATS2L
Spermatogenesis associated serine rich 2 like.
      
 0.677
COQ2
4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
      
 0.593
RPS6KA4
Ribosomal protein S6 kinase.
      
 0.592
PPP1R42
Protein phosphatase 1 regulatory subunit 42.
      
 0.526
KCTD18
Potassium channel tetramerization domain containing 18.
      
 0.491
VPS35L
VPS35 endosomal protein sorting factor like.
      
 0.487
MINDY4
MINDY lysine 48 deubiquitinase 4.
      
 0.487
GTF3A
General transcription factor IIIA.
      
 0.455
C2CD2
C2 calcium dependent domain containing 2.
      
 0.455
FAM228B
Uncharacterized protein.
      
 0.455
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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