STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UBR2E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1755 aa)    
Predicted Functional Partners:
TRIP12
Thyroid hormone receptor interactor 12.
   
 0.973
UBR4
Ubiquitin protein ligase E3 component n-recognin 4.
   
  
 0.818
ENSFCAP00000026617
Ubiquitin-like domain-containing protein.
   
 0.722
MYSM1
Myb like, SWIRM and MPN domains 1.
   
  
 0.702
UBE2A
Ubiquitin conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family.
   
 
 0.685
UBE2B
Ubiquitin conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family.
   
 
 0.685
USP34
Ubiquitin specific peptidase 34; Belongs to the peptidase C19 family.
   
  
 0.679
MRI1
Methylthioribose-1-phosphate isomerase 1; Belongs to the eIF-2B alpha/beta/delta subunits family.
      
 0.664
LOC101095082
Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
      
 0.664
UBR5
Ubiquitin protein ligase E3 component n-recognin 5.
   
  
 0.662
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: low (10%) [HD]