STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DOK6Docking protein 6. (331 aa)    
Predicted Functional Partners:
WDR6
WD repeat domain 6.
      
 0.691
RTTN
Rotatin.
      
 0.665
RET
Ret proto-oncogene; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.618
UBXN2B
UBX domain protein 2B.
      
 0.607
GFRA2
GDNF family receptor alpha-2; Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.
     
 0.573
GDNF
Glial cell derived neurotrophic factor.
     
 0.545
EXOSC1
Exosome component 1.
      
 0.541
CCDC63
Coiled-coil domain containing 63.
      
 0.538
ABCF1
ATP binding cassette subfamily F member 1.
      
 0.532
ACYP1
Acylphosphatase.
      
 0.531
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.