STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF6Rac/Cdc42 guanine nucleotide exchange factor 6. (775 aa)    
Predicted Functional Partners:
PAK1
Non-specific serine/threonine protein kinase.
    
 0.996
PAK3
P21 (RAC1) activated kinase 3.
    
 0.995
GIT1
GIT ArfGAP 1.
    
 0.984
PAK2
Non-specific serine/threonine protein kinase.
    
 0.978
ARHGEF1
Rho guanine nucleotide exchange factor 1.
    
 0.961
PAK5
Non-specific serine/threonine protein kinase.
    
 0.961
PAK4
Non-specific serine/threonine protein kinase.
    
 0.958
PAK6
Non-specific serine/threonine protein kinase.
    
 0.958
RAC2
Rac family small GTPase 2.
   
 0.956
PARVB
Parvin beta.
   
 0.943
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.