STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SWSAP1SWIM-type zinc finger 7 associated protein 1. (140 aa)    
Predicted Functional Partners:
ZSWIM7
Zinc finger SWIM-type containing 7.
    
 0.847
HSF2BP
Heat shock transcription factor 2 binding protein.
      
 0.807
FIGNL1
Fidgetin like 1; Belongs to the AAA ATPase family.
    
 
 0.788
BRCA2
Breast cancer type 2 susceptibility protein homolog; Involved in double-strand break repair and/or homologous recombination. Binds RAD51 and potentiates recombinational DNA repair by promoting assembly of RAD51 onto single-stranded DNA (ssDNA). Acts by targeting RAD51 to ssDNA over double-stranded DNA, enabling RAD51 to displace replication protein-A (RPA) from ssDNA and stabilizing RAD51- ssDNA filaments by blocking ATP hydrolysis. Part of a PALB2-scaffolded HR complex containing RAD51C and which is thought to play a role in DNA repair by HR. May participate in S phase checkpoint acti [...]
     
 0.777
MEIOB
Meiosis specific with OB-fold.
      
 0.772
SPIDR
Scaffold protein involved in DNA repair.
    
 
 0.762
PDS5B
PDS5 cohesin associated factor B.
      
 0.686
MSH4
DNA_MISMATCH_REPAIR_2 domain-containing protein.
      
 0.681
TRIP13
Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family.
    
 
 0.646
XRCC3
DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.
    
 
 0.639
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.