TTC6 protein (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

TTC6

TPR_REGION domain-containing protein. (1880 aa)

Predicted Functional Partners:

REC114

0.857

STXBP6

0.815

HCFC1

0.815

HCFC2

0.815

DNAAF4

0.803

SLC4A8

0.791

CLBA1

0.791

RNF144B

0.777

FAM83B

0.760

PRIM2

0.750

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLBA1	SLC4A8	ENSFCAP00000043003	ENSFCAP00000004075	Clathrin_bdg domain-containing protein.	Anion exchange protein.	0.791
CLBA1	TTC6	ENSFCAP00000043003	ENSFCAP00000004099	Clathrin_bdg domain-containing protein.	TPR_REGION domain-containing protein.	0.791
DNAAF4	TTC6	ENSFCAP00000024025	ENSFCAP00000004099	Dynein axonemal assembly factor 4.	TPR_REGION domain-containing protein.	0.803
FAM83B	PRIM2	ENSFCAP00000012463	ENSFCAP00000024705	Family with sequence similarity 83 member B.	DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.	0.752
FAM83B	REC114	ENSFCAP00000012463	ENSFCAP00000051724	Family with sequence similarity 83 member B.	REC114 meiotic recombination protein.	0.750
FAM83B	RNF144B	ENSFCAP00000012463	ENSFCAP00000030232	Family with sequence similarity 83 member B.	RBR-type E3 ubiquitin transferase.	0.609
FAM83B	STXBP6	ENSFCAP00000012463	ENSFCAP00000020770	Family with sequence similarity 83 member B.	Syntaxin binding protein 6.	0.663
FAM83B	TTC6	ENSFCAP00000012463	ENSFCAP00000004099	Family with sequence similarity 83 member B.	TPR_REGION domain-containing protein.	0.760
HCFC1	HCFC2	ENSFCAP00000027588	ENSFCAP00000048332	Host cell factor C1.	Host cell factor C2.	0.900
HCFC1	TTC6	ENSFCAP00000027588	ENSFCAP00000004099	Host cell factor C1.	TPR_REGION domain-containing protein.	0.815
HCFC2	HCFC1	ENSFCAP00000048332	ENSFCAP00000027588	Host cell factor C2.	Host cell factor C1.	0.900
HCFC2	TTC6	ENSFCAP00000048332	ENSFCAP00000004099	Host cell factor C2.	TPR_REGION domain-containing protein.	0.815
PRIM2	FAM83B	ENSFCAP00000024705	ENSFCAP00000012463	DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.	Family with sequence similarity 83 member B.	0.752
PRIM2	REC114	ENSFCAP00000024705	ENSFCAP00000051724	DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.	REC114 meiotic recombination protein.	0.750
PRIM2	RNF144B	ENSFCAP00000024705	ENSFCAP00000030232	DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.	RBR-type E3 ubiquitin transferase.	0.609
PRIM2	STXBP6	ENSFCAP00000024705	ENSFCAP00000020770	DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.	Syntaxin binding protein 6.	0.657
PRIM2	TTC6	ENSFCAP00000024705	ENSFCAP00000004099	DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.	TPR_REGION domain-containing protein.	0.750
REC114	FAM83B	ENSFCAP00000051724	ENSFCAP00000012463	REC114 meiotic recombination protein.	Family with sequence similarity 83 member B.	0.750
REC114	PRIM2	ENSFCAP00000051724	ENSFCAP00000024705	REC114 meiotic recombination protein.	DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.	0.750
REC114	RNF144B	ENSFCAP00000051724	ENSFCAP00000030232	REC114 meiotic recombination protein.	RBR-type E3 ubiquitin transferase.	0.703