STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FKBPLFKBP prolyl isomerase like. (349 aa)    
Predicted Functional Partners:
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component.
    
 0.791
ANKRD49
Ankyrin repeat domain 49.
   
 0.782
CDKN1A
Cyclin-dependent kinase inhibitor 1; May be involved in p53/TP53 mediated inhibition of cellular proliferation in response to DNA damage (By similarity). Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression (By similarity). Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1 (By similarity). At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex (By similarity). Inhibits [...]
   
 0.744
ZNF24
Zinc finger protein 24.
   
 0.676
ISM1
Isthmin 1.
   
  
 0.639
FBXL2
F-box and leucine rich repeat protein 2.
   
  
 0.625
FKBP15
Peptidylprolyl isomerase.
    
 
 0.622
APH1A
Aph-1 homolog A, gamma-secretase subunit.
      
 0.610
GTSE1
G2 and S-phase expressed 1.
     
 0.587
ARHGAP18
Rho GTPase activating protein 18.
   
  
 0.579
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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