STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa)    
Predicted Functional Partners:
PIK3R5
Phosphoinositide-3-kinase regulatory subunit 5.
   
 0.999
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.987
PIK3R2
Phosphoinositide-3-kinase regulatory subunit 2.
    
 0.983
PIK3R3
Uncharacterized protein.
    
 0.982
HRAS
HRas proto-oncogene, GTPase.
   
 0.966
KRAS
Uncharacterized protein.
   
 0.966
NRAS
NRAS proto-oncogene, GTPase.
   
 0.966
LYN
Tyrosine-protein kinase.
    
 0.963
PDPK1
3-phosphoinositide dependent protein kinase 1.
   
 0.962
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.
    
0.962
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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