STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRRX2Paired related homeobox 2. (260 aa)    
Predicted Functional Partners:
FKBP10
Peptidylprolyl isomerase.
   
  
 0.642
EFEMP2
EGF containing fibulin extracellular matrix protein 2.
   
 
 0.625
MRGPRF
MAS related GPR family member F; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.620
LMBR1
Limb development membrane protein 1; Belongs to the LIMR family.
      
 0.566
TGFB1I1
Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways.
    
 
 0.556
COPZ2
Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.
      
 0.545
ATOH8
Atonal bHLH transcription factor 8.
    
 
 0.543
QSOX2
Sulfhydryl oxidase.
      
 0.541
HMG20A
High mobility group 20A.
    
 
 0.537
CD4H9orf78
Chromosome D4 C9orf78 homolog.
      
 0.445
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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