SIVA1 protein (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SIVA1

Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis. (175 aa)

Predicted Functional Partners:

BCL2L1

0.942

BCL2

0.912

PKIA

0.693

TMEM121

0.653

NOL3

0.633

CD27

0.624

TRIP6

0.585

MAGI3

0.554

RAD18

0.529

MRPL45

0.518

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL2	BCL2L1	ENSFCAP00000062072	ENSFCAP00000059067	BCL2 apoptosis regulator.	BCL2 like 1.	0.983
BCL2	SIVA1	ENSFCAP00000062072	ENSFCAP00000004580	BCL2 apoptosis regulator.	Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.	0.912
BCL2L1	BCL2	ENSFCAP00000059067	ENSFCAP00000062072	BCL2 like 1.	BCL2 apoptosis regulator.	0.983
BCL2L1	SIVA1	ENSFCAP00000059067	ENSFCAP00000004580	BCL2 like 1.	Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.	0.942
CD27	SIVA1	ENSFCAP00000061814	ENSFCAP00000004580	CD27 molecule.	Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.	0.624
MAGI3	SIVA1	ENSFCAP00000030857	ENSFCAP00000004580	Membrane associated guanylate kinase, WW and PDZ domain containing 3.	Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.	0.554
MAGI3	TRIP6	ENSFCAP00000030857	ENSFCAP00000006363	Membrane associated guanylate kinase, WW and PDZ domain containing 3.	Thyroid hormone receptor interactor 6.	0.605
MRPL45	SIVA1	ENSFCAP00000039259	ENSFCAP00000004580	Mitochondrial ribosomal protein L45.	Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.	0.518
NOL3	SIVA1	ENSFCAP00000060422	ENSFCAP00000004580	Nucleolar protein 3.	Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.	0.633
PKIA	SIVA1	ENSFCAP00000029162	ENSFCAP00000004580	cAMP-dependent protein kinase inhibitor alpha.	Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.	0.693
RAD18	SIVA1	ENSFCAP00000024507	ENSFCAP00000004580	RAD18 E3 ubiquitin protein ligase.	Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.	0.529
SIVA1	BCL2	ENSFCAP00000004580	ENSFCAP00000062072	Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.	BCL2 apoptosis regulator.	0.912
SIVA1	BCL2L1	ENSFCAP00000004580	ENSFCAP00000059067	Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.	BCL2 like 1.	0.942
SIVA1	CD27	ENSFCAP00000004580	ENSFCAP00000061814	Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.	CD27 molecule.	0.624
SIVA1	MAGI3	ENSFCAP00000004580	ENSFCAP00000030857	Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.	Membrane associated guanylate kinase, WW and PDZ domain containing 3.	0.554
SIVA1	MRPL45	ENSFCAP00000004580	ENSFCAP00000039259	Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.	Mitochondrial ribosomal protein L45.	0.518
SIVA1	NOL3	ENSFCAP00000004580	ENSFCAP00000060422	Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.	Nucleolar protein 3.	0.633
SIVA1	PKIA	ENSFCAP00000004580	ENSFCAP00000029162	Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.	cAMP-dependent protein kinase inhibitor alpha.	0.693
SIVA1	RAD18	ENSFCAP00000004580	ENSFCAP00000024507	Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.	RAD18 E3 ubiquitin protein ligase.	0.529
SIVA1	TMEM121	ENSFCAP00000004580	ENSFCAP00000044150	Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.	Transmembrane protein 121.	0.653

page 1 of 2

Server load: low (40%) [HD]

Permalink

Network

Cooccurrence

Experiments

Neighborhood

Databases

Fusion

Textmining

Coexpression

© STRING Consortium 2025

Credits

Access

Info

About