STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYCBP2MYC binding protein 2. (4675 aa)    
Predicted Functional Partners:
FBXO45
F-box protein 45.
    
 
 0.931
FBXL3
F-box and leucine rich repeat protein 3.
 
    
 0.713
UBA52
Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...]
    
   0.701
HERC1
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1.
   
 
0.679
RIMS3
Regulating synaptic membrane exocytosis 3.
      
 0.676
CCS
Copper chaperone for superoxide dismutase.
      
 0.638
BIRC6
Baculoviral IAP repeat containing 6.
   
 
 0.625
SPSB3
SplA/ryanodine receptor domain and SOCS box containing 3.
    
 
 0.624
SPSB2
SplA/ryanodine receptor domain and SOCS box containing 2.
    
 
 0.624
SPSB1
SplA/ryanodine receptor domain and SOCS box containing 1.
    
 
 0.624
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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