STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRIK3Glutamate ionotropic receptor kainate type subunit 3. (919 aa)    
Predicted Functional Partners:
GRIK4
Glutamate ionotropic receptor kainate type subunit 4.
  
 
0.912
GRIK5
Glutamate ionotropic receptor kainate type subunit 5.
  
 
0.874
GRIK2
Glutamate ionotropic receptor kainate type subunit 2.
  
0.817
GRIA1
Glutamate ionotropic receptor AMPA type subunit 1.
  
0.800
SCN4B
Sodium voltage-gated channel beta subunit 4.
     
 0.754
DLG4
Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.
   
 0.730
DLG3
Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family.
   
 0.726
PLAC8L1
PLAC8 like 1.
      
 0.685
SCN11A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
     
 0.680
GRIA2
Glutamate ionotropic receptor AMPA type subunit 2.
  
0.674
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.