STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCNN1GSodium channel epithelial 1 gamma subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (646 aa)    
Predicted Functional Partners:
SCNN1B
Sodium channel epithelial 1 beta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
  
0.999
SCNN1A
Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
  
0.987
NEDD4L
NEDD4 like E3 ubiquitin protein ligase.
    
 0.975
SCNN1D
Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
  
0.939
NEDD4
NEDD4 E3 ubiquitin protein ligase.
    
 0.787
HSD11B2
Hydroxysteroid 11-beta dehydrogenase 2.
   
  
 0.671
NIM1K
NIM1 serine/threonine protein kinase; Belongs to the protein kinase superfamily.
      
 0.667
ATP13A3
Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
      
 0.652
SCN3B
Sodium voltage-gated channel beta subunit 3.
     
 0.647
KCNH8
Potassium voltage-gated channel subfamily H member 8.
   
  
 0.614
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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