STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)    
Predicted Functional Partners:
TGFBR1
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    
 0.999
TGFBR2
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
   
 0.998
LTBP1
Latent transforming growth factor beta binding protein 1.
   
 0.996
DCN
Decorin; May affect the rate of fibrils formation.
    
 0.985
TGFB3
Transforming growth factor beta; Belongs to the TGF-beta family.
     
0.961
FMOD
Fibromodulin.
    
 0.951
ITGAV
Integrin subunit alpha V; Belongs to the integrin alpha chain family.
   
 0.949
SMAD2
Mothers against decapentaplegic homolog.
    
 0.925
ITGB6
Integrin beta; Belongs to the integrin beta chain family.
   
 0.924
LOC105261327
Left-right determination factor.
     
 0.924
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.