STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)    
Predicted Functional Partners:
ICMT
Protein-S-isoprenylcysteine O-methyltransferase.
    
 0.980
FNTA
Farnesyltransferase, CAAX box, alpha.
     
 0.942
RCE1
Ras converting CAAX endopeptidase 1.
    
 
 0.941
FNTB
Protein farnesyltransferase subunit beta; Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.
     
 0.933
LMNB2
Lamin B2; Belongs to the intermediate filament family.
    
 
 0.738
LMNB1
Lamin B1; Belongs to the intermediate filament family.
    
 
 0.677
PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1.
      
 0.656
LMNA
Lamin A/C; Belongs to the intermediate filament family.
    
 
 0.636
CRTAP
Cartilage associated protein.
   
  
 0.617
ADAMTS2
ADAM metallopeptidase with thrombospondin type 1 motif 2.
      
 0.610
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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