STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAEPBeta-lactoglobulin-1; Lactoglobulin is the primary component of whey, it binds retinol and is probably involved in the transport of that molecule. (180 aa)    
Predicted Functional Partners:
GOSR2
Uncharacterized protein; Belongs to the glycosyl hydrolase 22 family.
   
  
 0.799
LYZL4
Lysozyme like 4; Belongs to the glycosyl hydrolase 22 family.
   
  
 0.786
SPACA3
Sperm acrosome associated 3; Belongs to the glycosyl hydrolase 22 family.
   
  
 0.778
LALBA
Alpha-lactalbumin; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N- acetylglucosamine of the oligosaccharide chains in glycoproteins.
   
  
 0.665
CSN3
Kappa-casein; Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk; Belongs to the kappa-casein family.
   
 0.567
CDC73
Cell division cycle 73.
   
 0.547
CSN2
Beta-casein; Important role in determination of the surface properties of the casein micelles.
   
  
 0.520
TOP2B
DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.
   
  
 0.516
PAF1
PAF1 homolog, Paf1/RNA polymerase II complex component.
   
 0.514
C8B
Complement C8 beta chain.
   
 0.463
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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