STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UNC13DUnc-13 homolog D. (1091 aa)    
Predicted Functional Partners:
STX11
Syntaxin 11; Belongs to the syntaxin family.
   
  
 0.773
STXBP2
Syntaxin binding protein 2; Belongs to the STXBP/unc-18/SEC1 family.
      
 0.747
RAB27A
RAB27A, member RAS oncogene family.
    
 
 0.600
SH2D1A
SH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2.
   
  
 0.590
LYST
Lysosomal trafficking regulator.
   
  
 0.564
AP3B1
AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.
      
 0.515
AJAP1
Adherens junctions associated protein 1.
      
 0.455
STX19
Syntaxin 19; Belongs to the syntaxin family.
      
 0.442
STRIP1
Striatin interacting protein 1.
      
 0.436
CARD11
Caspase recruitment domain family member 11.
   
  
 0.418
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.