ITGB7 protein (Felis catus) - STRING interaction network

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Predicted Interactions

gene neighborhood

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textmining

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protein homology

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Score

ITGB7

Integrin beta; Belongs to the integrin beta chain family. (797 aa)

Predicted Functional Partners:

ITGA4

0.999

ITGAE

0.985

MADCAM1

0.982

SRC

0.973

PTK2

0.959

FN1

0.948

VCAM1

0.937

CAV1

0.923

ACTG1

0.917

TLN2

0.917

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTG1	CAV1	ENSFCAP00000006307	ENSFCAP00000029296	Actin gamma 1.	Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...]	0.482
ACTG1	ITGA4	ENSFCAP00000006307	ENSFCAP00000010074	Actin gamma 1.	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	0.909
ACTG1	ITGB7	ENSFCAP00000006307	ENSFCAP00000005449	Actin gamma 1.	Integrin beta; Belongs to the integrin beta chain family.	0.917
ACTG1	PTK2	ENSFCAP00000006307	ENSFCAP00000033797	Actin gamma 1.	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.417
ACTG1	SRC	ENSFCAP00000006307	ENSFCAP00000041142	Actin gamma 1.	Tyrosine-protein kinase.	0.455
CAV1	ACTG1	ENSFCAP00000029296	ENSFCAP00000006307	Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...]	Actin gamma 1.	0.482
CAV1	ITGB7	ENSFCAP00000029296	ENSFCAP00000005449	Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...]	Integrin beta; Belongs to the integrin beta chain family.	0.923
CAV1	PTK2	ENSFCAP00000029296	ENSFCAP00000033797	Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...]	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.410
CAV1	SRC	ENSFCAP00000029296	ENSFCAP00000041142	Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...]	Tyrosine-protein kinase.	0.987
FN1	ITGA4	ENSFCAP00000008544	ENSFCAP00000010074	Fibronectin 1.	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	0.919
FN1	ITGAE	ENSFCAP00000008544	ENSFCAP00000007343	Fibronectin 1.	Integrin subunit alpha E; Belongs to the integrin alpha chain family.	0.672
FN1	ITGB7	ENSFCAP00000008544	ENSFCAP00000005449	Fibronectin 1.	Integrin beta; Belongs to the integrin beta chain family.	0.948
FN1	PTK2	ENSFCAP00000008544	ENSFCAP00000033797	Fibronectin 1.	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.746
ITGA4	ACTG1	ENSFCAP00000010074	ENSFCAP00000006307	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	Actin gamma 1.	0.909
ITGA4	FN1	ENSFCAP00000010074	ENSFCAP00000008544	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	Fibronectin 1.	0.919
ITGA4	ITGAE	ENSFCAP00000010074	ENSFCAP00000007343	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	Integrin subunit alpha E; Belongs to the integrin alpha chain family.	0.681
ITGA4	ITGB7	ENSFCAP00000010074	ENSFCAP00000005449	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	Integrin beta; Belongs to the integrin beta chain family.	0.999
ITGA4	MADCAM1	ENSFCAP00000010074	ENSFCAP00000007253	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	Mucosal vascular addressin cell adhesion molecule 1.	0.986
ITGA4	PTK2	ENSFCAP00000010074	ENSFCAP00000033797	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.941
ITGA4	SRC	ENSFCAP00000010074	ENSFCAP00000041142	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	Tyrosine-protein kinase.	0.924