STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GFI1Growth factor independent 1 transcriptional repressor. (422 aa)    
Predicted Functional Partners:
ATOH1
Atonal bHLH transcription factor 1.
    
 
 0.844
CEBPE
CCAAT/enhancer-binding protein.
    
 0.720
MYO7A
Myosin VIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 
 0.689
POU4F1
POU domain protein.
      
 0.661
RUNX1
Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
   
 0.653
SPDEF
SAM pointed domain containing ETS transcription factor.
    
 
 0.650
GATA2
GATA binding protein 2.
   
 0.609
GATA1
GATA binding protein 1.
   
 0.585
POU4F3
POU domain protein.
      
 0.540
MYO6
Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 
 0.538
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.