STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IRF3Interferon regulatory factor 3. (420 aa)    
Predicted Functional Partners:
CREBBP
CREB binding protein.
    
 0.999
TBK1
TANK binding kinase 1.
   
 0.999
IRF7
Interferon regulatory factor 7.
     
0.997
EP300
E1A binding protein p300.
    
 0.993
IFNB1
Interferon beta; Has antiviral, antibacterial and anticancer activities.
     
 0.988
IKBKE
Inhibitor of nuclear factor kappa B kinase subunit epsilon.
   
 0.988
ISG15
ISG15 ubiquitin like modifier.
   
 0.988
TICAM1
Toll like receptor adaptor molecule 1.
    
 0.985
PIN1
Peptidyl-prolyl cis-trans isomerase.
   
 0.981
STING1
Stimulator of interferon genes.
   
 0.967
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.