STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NR1I2Nuclear receptor subfamily 1 group I member 2. (434 aa)    
Predicted Functional Partners:
NCOA1
Nuclear receptor coactivator.
    
 0.943
RXRA
Retinoid X receptor alpha.
    
0.859
INPP5D
Inositol polyphosphate-5-phosphatase D.
      
 0.800
GBA
Glucosylceramidase.
      
 0.795
LOC101092602
FAD-binding PCMH-type domain-containing protein.
   
 
 0.792
ADGRA3
Adhesion G protein-coupled receptor A3; Belongs to the G-protein coupled receptor 2 family.
    
 
 0.765
CYP1A2
Cytochrome P450 1A2; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E [...]
   
 
 0.718
NCOR2
Nuclear receptor corepressor 2.
    
 0.677
SGK2
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
   
 
 0.673
RXRG
Retinoid X receptor gamma.
    
0.673
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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