STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CREBBPCREB binding protein. (2444 aa)    
Predicted Functional Partners:
HIF1A
Hypoxia inducible factor 1 subunit alpha.
    
 0.999
EP300
E1A binding protein p300.
  
0.999
IRF3
Interferon regulatory factor 3.
    
 0.999
CREB1
cAMP responsive element binding protein 1.
   
 0.998
CTNNB1
Catenin beta 1.
    
 0.997
NCOA3
Nuclear receptor coactivator.
   
 0.995
NCOA1
Nuclear receptor coactivator.
   
 0.995
RBPJ
Recombination signal binding protein for immunoglobulin kappa J region.
    
 0.993
RELA
RELA proto-oncogene, NF-kB subunit.
    
 0.987
STAT1
Signal transducer and activator of transcription.
    
 0.985
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.