STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HSPB6Heat shock protein family B (small) member 6; Belongs to the small heat shock protein (HSP20) family. (161 aa)    
Predicted Functional Partners:
MAPKAPK5
MAPK activated protein kinase 5.
    
 0.730
SFN
Stratifin; Belongs to the 14-3-3 family.
   
 
 0.725
MAPKAPK2
MAPK activated protein kinase 2.
   
 0.721
MAPKAPK3
MAPK activated protein kinase 3; Belongs to the protein kinase superfamily.
   
 0.720
PDC
Phosducin; Inhibits the transcriptional activation activity of the cone- rod homeobox CRX (By similarity). May participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism; Belongs to the phosducin family.
      
 0.708
CRYBA1
Crystallin beta A1; Belongs to the beta/gamma-crystallin family.
   
 
 0.704
CRYAB
Crystallin alpha B; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
  
0.628
HSPA1L
Heat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family.
   
 0.594
ENSFCAP00000041941
Uncharacterized protein; Belongs to the heat shock protein 70 family.
   
 0.594
TBC1D21
TBC1 domain family member 21.
      
 0.572
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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