Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRRG3Proline rich and Gla domain 3. (231 aa)    
Predicted Functional Partners:
NEDD4L
NEDD4 like E3 ubiquitin protein ligase.
    
   0.730
NEDD4
NEDD4 E3 ubiquitin protein ligase.
    
   0.709
NDFIP1
Nedd4 family interacting protein 1.
    
   0.635
TBCE
Uncharacterized protein.
      
 0.539
CCDC116
Coiled-coil domain containing 116.
      
 0.512
LRRC52
Leucine rich repeat containing 52.
      
 0.442
AKAP12
A-kinase anchoring protein 12.
      
 0.435
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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