STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DMRT1Doublesex and mab-3 related transcription factor 1. (378 aa)    
Predicted Functional Partners:
AMH
Anti-Mullerian hormone.
      
 0.753
SOX9
SRY-box transcription factor 9.
    
 0.712
REC8
REC8 meiotic recombination protein.
      
 0.676
CYP17A1
Steroid 17-alpha-hydroxylase/17,20 lyase; A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol. Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, [...]
      
 0.669
FOXL2
Forkhead box L2.
      
 0.668
NANOS2
Nanos C2HC-type zinc finger 2; Belongs to the nanos family.
    
 
 0.636
STK31
Serine/threonine kinase 31.
   
  
 0.612
DAZL
Deleted in azoospermia like.
   
 
 0.610
GATA4
GATA binding protein 4.
   
 0.597
NANOS3
Nanos C2HC-type zinc finger 3; Belongs to the nanos family.
    
 
 0.595
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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