STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IQGAP3IQ motif containing GTPase activating protein 3. (1630 aa)    
Predicted Functional Partners:
CDC42-2
Uncharacterized protein.
   
 0.975
RAC2
Rac family small GTPase 2.
   
 0.954
IQGAP1
IQ motif containing GTPase activating protein 1.
  
  
0.943
KIF20A
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
 0.838
HJURP
Holliday junction recognition protein.
   
  
 0.813
ESPL1
Extra spindle pole bodies like 1, separase.
   
    0.806
ITSN2
Intersectin 2.
    
 0.794
CDC42
Uncharacterized protein.
   
 0.763
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B.
   
  
 0.730
CNKSR2
Connector enhancer of kinase suppressor of Ras 2.
     
 0.721
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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