LRIG3 protein (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

LRIG3

Leucine rich repeats and immunoglobulin like domains 3. (1122 aa)

Predicted Functional Partners:

MET

0.773

FAM160A1

0.692

GNAT3

0.675

BRINP1

0.674

SLC34A2

0.665

ROS1

0.665

CNPY4

0.650

PRKCI

0.644

PTN

0.638

GPR26

0.638

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRINP1	FAM160A1	ENSFCAP00000039813	ENSFCAP00000021051	BMP/retinoic acid inducible neural specific 1.	Family with sequence similarity 160 member A1.	0.752
BRINP1	GPR26	ENSFCAP00000039813	ENSFCAP00000041717	BMP/retinoic acid inducible neural specific 1.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.757
BRINP1	LRIG3	ENSFCAP00000039813	ENSFCAP00000006165	BMP/retinoic acid inducible neural specific 1.	Leucine rich repeats and immunoglobulin like domains 3.	0.674
CNPY4	LRIG3	ENSFCAP00000003287	ENSFCAP00000006165	Canopy FGF signaling regulator 4.	Leucine rich repeats and immunoglobulin like domains 3.	0.650
FAM160A1	BRINP1	ENSFCAP00000021051	ENSFCAP00000039813	Family with sequence similarity 160 member A1.	BMP/retinoic acid inducible neural specific 1.	0.752
FAM160A1	GPR26	ENSFCAP00000021051	ENSFCAP00000041717	Family with sequence similarity 160 member A1.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.754
FAM160A1	LRIG3	ENSFCAP00000021051	ENSFCAP00000006165	Family with sequence similarity 160 member A1.	Leucine rich repeats and immunoglobulin like domains 3.	0.692
GNAT3	LRIG3	ENSFCAP00000026394	ENSFCAP00000006165	G protein subunit alpha transducin 3.	Leucine rich repeats and immunoglobulin like domains 3.	0.675
GNAT3	MET	ENSFCAP00000026394	ENSFCAP00000060432	G protein subunit alpha transducin 3.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.422
GPR26	BRINP1	ENSFCAP00000041717	ENSFCAP00000039813	G_PROTEIN_RECEP_F1_2 domain-containing protein.	BMP/retinoic acid inducible neural specific 1.	0.757
GPR26	FAM160A1	ENSFCAP00000041717	ENSFCAP00000021051	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Family with sequence similarity 160 member A1.	0.754
GPR26	LRIG3	ENSFCAP00000041717	ENSFCAP00000006165	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Leucine rich repeats and immunoglobulin like domains 3.	0.638
LRIG3	BRINP1	ENSFCAP00000006165	ENSFCAP00000039813	Leucine rich repeats and immunoglobulin like domains 3.	BMP/retinoic acid inducible neural specific 1.	0.674
LRIG3	CNPY4	ENSFCAP00000006165	ENSFCAP00000003287	Leucine rich repeats and immunoglobulin like domains 3.	Canopy FGF signaling regulator 4.	0.650
LRIG3	FAM160A1	ENSFCAP00000006165	ENSFCAP00000021051	Leucine rich repeats and immunoglobulin like domains 3.	Family with sequence similarity 160 member A1.	0.692
LRIG3	GNAT3	ENSFCAP00000006165	ENSFCAP00000026394	Leucine rich repeats and immunoglobulin like domains 3.	G protein subunit alpha transducin 3.	0.675
LRIG3	GPR26	ENSFCAP00000006165	ENSFCAP00000041717	Leucine rich repeats and immunoglobulin like domains 3.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.638
LRIG3	MET	ENSFCAP00000006165	ENSFCAP00000060432	Leucine rich repeats and immunoglobulin like domains 3.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.773
LRIG3	PRKCI	ENSFCAP00000006165	ENSFCAP00000025222	Leucine rich repeats and immunoglobulin like domains 3.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.644
LRIG3	PTN	ENSFCAP00000006165	ENSFCAP00000022452	Leucine rich repeats and immunoglobulin like domains 3.	Pleiotrophin.	0.638