STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CLIC6Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (589 aa)    
Predicted Functional Partners:
MTHFD1
Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1.
    
 
 0.616
EZR
Ezrin.
   
 0.585
NME5
NME/NM23 family member 5; Belongs to the NDK family.
   
  
 0.562
PDLIM3
PDZ and LIM domain 3.
   
  
 0.557
RDX
Radixin.
   
 0.537
RAP1A
RAP1A, member of RAS oncogene family.
   
  
 0.525
SLC12A7
Solute carrier family 12 member 7.
   
  
 0.524
SLC12A8
Solute carrier family 12 member 8.
   
  
 0.513
FUNDC2
FUN14 domain containing 2.
      
 0.505
SETD4
SET domain containing 4.
      
 0.476
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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