STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
THUMPD2THUMP domain containing 2. (503 aa)    
Predicted Functional Partners:
RGS1
Regulator of G protein signaling 1.
      
 0.750
KLF6
Kruppel like factor 6.
      
 0.705
TXNIP
Thioredoxin interacting protein.
      
 0.698
GADD45B
Growth arrest and DNA damage inducible beta.
      
 0.686
DHDDS
Alkyl transferase; Belongs to the UPP synthase family.
   
    0.580
NUS1
NUS1 dehydrodolichyl diphosphate synthase subunit.
   
    0.580
RPUSD1
RNA pseudouridine synthase domain containing 1.
  
 
 0.567
PNPT1
Polyribonucleotide nucleotidyltransferase 1.
  
    0.545
APMAP
Adipocyte plasma membrane associated protein.
  
    0.545
QTRT1
Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...]
  
  
 0.533
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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