| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BIRC3 | CHUK | ENSFCAP00000013003 | ENSFCAP00000060797 | Baculoviral IAP repeat containing 3. | Component of inhibitor of nuclear factor kappa B kinase complex. | 0.760 |
| BIRC3 | CYLD | ENSFCAP00000013003 | ENSFCAP00000030884 | Baculoviral IAP repeat containing 3. | CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. | 0.704 |
| BIRC3 | FADD | ENSFCAP00000013003 | ENSFCAP00000045141 | Baculoviral IAP repeat containing 3. | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. | 0.924 |
| BIRC3 | IKBKB | ENSFCAP00000013003 | ENSFCAP00000044529 | Baculoviral IAP repeat containing 3. | Inhibitor of nuclear factor kappa B kinase subunit beta. | 0.801 |
| BIRC3 | LTA | ENSFCAP00000013003 | ENSFCAP00000004152 | Baculoviral IAP repeat containing 3. | Tumor necrosis factor ligand 1E; Belongs to the tumor necrosis factor family. | 0.577 |
| BIRC3 | RIPK1 | ENSFCAP00000013003 | ENSFCAP00000013566 | Baculoviral IAP repeat containing 3. | Receptor interacting serine/threonine kinase 1. | 0.986 |
| BIRC3 | TNF | ENSFCAP00000013003 | ENSFCAP00000051032 | Baculoviral IAP repeat containing 3. | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] | 0.918 |
| BIRC3 | TNFRSF1A | ENSFCAP00000013003 | ENSFCAP00000006375 | Baculoviral IAP repeat containing 3. | TNF receptor superfamily member 1A. | 0.988 |
| BIRC3 | TNFRSF1B | ENSFCAP00000013003 | ENSFCAP00000003482 | Baculoviral IAP repeat containing 3. | TNF receptor superfamily member 1B. | 0.497 |
| BIRC3 | TRADD | ENSFCAP00000013003 | ENSFCAP00000045608 | Baculoviral IAP repeat containing 3. | TNFRSF1A associated via death domain. | 0.987 |
| CHUK | BIRC3 | ENSFCAP00000060797 | ENSFCAP00000013003 | Component of inhibitor of nuclear factor kappa B kinase complex. | Baculoviral IAP repeat containing 3. | 0.760 |
| CHUK | CYLD | ENSFCAP00000060797 | ENSFCAP00000030884 | Component of inhibitor of nuclear factor kappa B kinase complex. | CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. | 0.885 |
| CHUK | FADD | ENSFCAP00000060797 | ENSFCAP00000045141 | Component of inhibitor of nuclear factor kappa B kinase complex. | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. | 0.634 |
| CHUK | IKBKB | ENSFCAP00000060797 | ENSFCAP00000044529 | Component of inhibitor of nuclear factor kappa B kinase complex. | Inhibitor of nuclear factor kappa B kinase subunit beta. | 0.998 |
| CHUK | RIPK1 | ENSFCAP00000060797 | ENSFCAP00000013566 | Component of inhibitor of nuclear factor kappa B kinase complex. | Receptor interacting serine/threonine kinase 1. | 0.992 |
| CHUK | TNF | ENSFCAP00000060797 | ENSFCAP00000051032 | Component of inhibitor of nuclear factor kappa B kinase complex. | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] | 0.981 |
| CHUK | TNFRSF1A | ENSFCAP00000060797 | ENSFCAP00000006375 | Component of inhibitor of nuclear factor kappa B kinase complex. | TNF receptor superfamily member 1A. | 0.989 |
| CHUK | TRADD | ENSFCAP00000060797 | ENSFCAP00000045608 | Component of inhibitor of nuclear factor kappa B kinase complex. | TNFRSF1A associated via death domain. | 0.940 |
| CYLD | BIRC3 | ENSFCAP00000030884 | ENSFCAP00000013003 | CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. | Baculoviral IAP repeat containing 3. | 0.704 |
| CYLD | CHUK | ENSFCAP00000030884 | ENSFCAP00000060797 | CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. | Component of inhibitor of nuclear factor kappa B kinase complex. | 0.885 |
