node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LOC111556172 | MED1 | ENSFCAP00000006476 | ENSFCAP00000044432 | Uncharacterized protein. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.685 |
LOC111556172 | NCOA1 | ENSFCAP00000006476 | ENSFCAP00000042028 | Uncharacterized protein. | Nuclear receptor coactivator. | 0.679 |
LOC111556172 | NCOA2 | ENSFCAP00000006476 | ENSFCAP00000018792 | Uncharacterized protein. | Nuclear receptor coactivator. | 0.926 |
LOC111556172 | NCOA3 | ENSFCAP00000006476 | ENSFCAP00000013944 | Uncharacterized protein. | Nuclear receptor coactivator. | 0.679 |
LOC111556172 | NCOR2 | ENSFCAP00000006476 | ENSFCAP00000024270 | Uncharacterized protein. | Nuclear receptor corepressor 2. | 0.679 |
LOC111556172 | NR1H2 | ENSFCAP00000006476 | ENSFCAP00000008507 | Uncharacterized protein. | Nuclear receptor subfamily 1 group H member 2. | 0.756 |
LOC111556172 | NR1H3 | ENSFCAP00000006476 | ENSFCAP00000051861 | Uncharacterized protein. | Nuclear receptor subfamily 1 group H member 3. | 0.926 |
LOC111556172 | NR1H4 | ENSFCAP00000006476 | ENSFCAP00000006012 | Uncharacterized protein. | Nuclear receptor subfamily 1 group H member 4. | 0.690 |
LOC111556172 | PPARG | ENSFCAP00000006476 | ENSFCAP00000050722 | Uncharacterized protein. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.744 |
LOC111556172 | RARB | ENSFCAP00000006476 | ENSFCAP00000009659 | Uncharacterized protein. | Retinoic acid receptor beta. | 0.851 |
MED1 | LOC111556172 | ENSFCAP00000044432 | ENSFCAP00000006476 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Uncharacterized protein. | 0.685 |
MED1 | NCOA1 | ENSFCAP00000044432 | ENSFCAP00000042028 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor coactivator. | 0.671 |
MED1 | NCOA2 | ENSFCAP00000044432 | ENSFCAP00000018792 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor coactivator. | 0.577 |
MED1 | NCOA3 | ENSFCAP00000044432 | ENSFCAP00000013944 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor coactivator. | 0.964 |
MED1 | NCOR2 | ENSFCAP00000044432 | ENSFCAP00000024270 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor corepressor 2. | 0.581 |
MED1 | NR1H2 | ENSFCAP00000044432 | ENSFCAP00000008507 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor subfamily 1 group H member 2. | 0.751 |
MED1 | NR1H3 | ENSFCAP00000044432 | ENSFCAP00000051861 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor subfamily 1 group H member 3. | 0.751 |
MED1 | NR1H4 | ENSFCAP00000044432 | ENSFCAP00000006012 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor subfamily 1 group H member 4. | 0.783 |
MED1 | PPARG | ENSFCAP00000044432 | ENSFCAP00000050722 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.970 |
MED1 | RARB | ENSFCAP00000044432 | ENSFCAP00000009659 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Retinoic acid receptor beta. | 0.698 |