STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PITX2Paired like homeodomain 2. (446 aa)    
Predicted Functional Partners:
FOXC1
Forkhead box C1.
    
 
 0.769
CTNNB1
Catenin beta 1.
    
 
 0.713
ISL1
ISL LIM homeobox 1.
    
 
 0.633
FOXE3
Forkhead box E3.
   
 
 0.615
FOXC2
Forkhead box C2.
    
 
 0.589
SH3PXD2B
SH3 and PX domains 2B.
      
 0.577
PHACTR4
Phosphatase and actin regulator.
      
 0.537
FOXH1
Forkhead box H1.
    
 
 0.536
ISL2
ISL LIM homeobox 2.
    
 
 0.532
MSX2
Msh homeobox 2.
    
 
0.509
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.