STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DMPKDM1 protein kinase. (801 aa)    
Predicted Functional Partners:
CELF1
CUGBP Elav-like family member 1.
    
 
 0.875
PRICKLE3
Prickle planar cell polarity protein 3.
   
 0.846
MBNL1
Muscleblind like splicing regulator 1.
      
 0.753
MBNL3
Muscleblind like splicing regulator 3.
      
 0.743
MBNL2
Muscleblind like splicing regulator 2.
      
 0.741
RND1
Rho family GTPase 1.
   
 0.650
RHOA
Ras homolog family member A.
   
 0.650
RND3
Rho family GTPase 3.
   
 0.650
PIGA
Phosphatidylinositol glycan anchor biosynthesis class A.
   
 
 0.642
TES
Testin; Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor (By similarity); Belongs to the prickle / espinas / testin family.
   
 0.630
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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