STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GAB2GRB2 associated binding protein 2. (678 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
    
 0.998
PTPN11
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
    
 0.978
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.975
PIK3R2
Phosphoinositide-3-kinase regulatory subunit 2.
    
 0.946
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
     
 0.942
PIK3R3
Uncharacterized protein.
    
 0.942
SOS2
SOS Ras/Rho guanine nucleotide exchange factor 2.
     
 0.940
EGFR
Receptor protein-tyrosine kinase.
    
 0.937
SYK
Spleen associated tyrosine kinase.
    
 0.934
LYN
Tyrosine-protein kinase.
    
 0.934
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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