STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC40A1Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (576 aa)    
Predicted Functional Partners:
HEPH
Hephaestin; Belongs to the multicopper oxidase family.
    
 0.984
HAMP
Hepcidin antimicrobial peptide.
    
 
 0.913
LOC101080399
Uncharacterized protein; Belongs to the multicopper oxidase family.
    
 0.876
CP
Ceruloplasmin; Belongs to the multicopper oxidase family.
    
 0.876
HFE
Homeostatic iron regulator; Belongs to the MHC class I family.
      
 0.755
HEPHL1
Hephaestin like 1; Belongs to the multicopper oxidase family.
    
 0.656
TFR2
Transferrin receptor 2.
      
 0.644
ATP13A3
Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
      
 0.614
ABCB6
ATP binding cassette subfamily B member 6.
      
 0.590
SLC11A2
Solute carrier family 11 member 2.
      
 0.546
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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