STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDPNPodoplanin. (163 aa)    
Predicted Functional Partners:
CLEC1B
C-type lectin domain family 1 member B.
    
 0.986
CLEC1A
C-type lectin domain family 1 member A.
    
 0.895
CLEC9A
C-type lectin domain containing 9A.
    
 0.758
LYVE1
Lymphatic vessel endothelial hyaluronan receptor 1.
    
 
 0.679
PECAM1
Platelet and endothelial cell adhesion molecule 1.
      
 0.611
VEGFC
Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family.
      
 0.589
LCP2
Lymphocyte cytosolic protein 2.
   
 0.579
PROX1
Prospero homeobox 1.
      
 0.562
PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
     
 0.554
PTPN6
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
   
 
 0.547
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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