STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CASP14Caspase 14; Belongs to the peptidase C14A family. (318 aa)    
Predicted Functional Partners:
XIAP
X-linked inhibitor of apoptosis.
   
 0.807
BLMH
Bleomycin hydrolase; Belongs to the peptidase C1 family.
    
 
 0.796
APAF1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
    
 0.737
CENPN
Centromere protein N.
   
 0.733
SERPINB12
Serpin family B member 12; Belongs to the serpin family.
   
 
 0.725
CENPI
Centromere protein I.
   
 0.713
CENPP
Uncharacterized protein.
   
 0.703
CENPQ
Centromere protein Q.
   
 0.691
CENPM
Centromere protein M.
   
 0.679
CENPT
Centromere protein T.
   
 0.663
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.