Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CKBCreatine kinase B; Belongs to the ATP:guanido phosphotransferase family. (480 aa)    
Predicted Functional Partners:
GOT1
Aspartate aminotransferase.
   
 
 0.939
GOT2
Aspartate aminotransferase.
   
 
 0.937
GAMT
Guanidinoacetate N-methyltransferase.
     
 0.925
CKM
Creatine kinase, M-type; Belongs to the ATP:guanido phosphotransferase family.
     
  0.856
CKMT2
Creatine kinase, mitochondrial 2; Belongs to the ATP:guanido phosphotransferase family.
   
  0.772
CKMT1A
Uncharacterized protein; Belongs to the ATP:guanido phosphotransferase family.
   
  0.772
ASB9
Ankyrin repeat and SOCS box containing 9.
   
 0.756
ALB
Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]
      
 0.751
SGCA
Sarcoglycan alpha.
   
  
 0.732
MYLPF
Myosin light chain, phosphorylatable, fast skeletal muscle.
   
 
 0.723
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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