STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF1Rho guanine nucleotide exchange factor 1. (1069 aa)    
Predicted Functional Partners:
GNA13
G protein subunit alpha 13.
    
 0.999
RHOA
Ras homolog family member A.
   
 0.990
GNA12
G protein subunit alpha 12.
    
 0.982
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor 6.
    
 0.961
PTK2
Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 
 0.938
ARHGEF11
Rho guanine nucleotide exchange factor 11.
     
0.938
ARHGEF7
Rho guanine nucleotide exchange factor 7.
    
 0.937
AKAP13
Uncharacterized protein.
   
0.937
PTK2B
Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 
 0.936
ARHGEF12
Rho guanine nucleotide exchange factor 12.
  
  
0.934
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.